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Showing posts with label malaria. Show all posts
Showing posts with label malaria. Show all posts

Friday, September 3, 2010

Novel anti-malarial drug candidate discovered .

(ANI)Researchers discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria.

Scientists at the Novartis Institute for Tropical Diseases (NITD), achieved the above feat in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute.

The findings demonstrate that the antimalarial candidate, spiroindolone NITD609, is effective against both strains of the malaria parasite, Plasmodium (P.) falciparum and P. vivax.

Through a novel mechanism NITD609 rapidly clears plasmodium in a malaria mouse model and shows pharmacological properties compatible with a once-daily dosing regimen.